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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
08/03/2023 |
Actualizado : |
15/03/2023 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
RAMOS, Z.; GARRICK , D. J.; BLAIR, H. T.; VERA, B.; CIAPPESONI, G.; KENYON, P. R. |
Afiliación : |
ZULLY MARGOT RAMOS ALVEZ, School of Agriculture and Environment, Massey University, Palmerston North 4410, New Zealand; DORIAN J. GARRICK, School of Agriculture and Environment, Massey University, Palmerston North 4410, New Zealand; HUGH T. BLAIR, School of Agriculture and Environment, Massey University, Palmerston North 4410, New Zealand; BRENDA VERA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CARLOS GABRIEL CIAPPESONI SCARONE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; PAUL R. KENYON, School of Agriculture and Environment, Massey University, Palmerston North 4410, New Zealand. |
Título : |
Genomic regions associated with wool, growth and reproduction traits in Uruguayan Merino Sheep. |
Fecha de publicación : |
2023 |
Fuente / Imprenta : |
Genes, 2023, volume 14, issue 1, article 167. OPEN ACCESS. doi: https://doi.org/10.3390/genes14010167 |
ISSN : |
2073-4425 |
DOI : |
10.3390/genes14010167 |
Idioma : |
Inglés |
Notas : |
Article history: Received 13 December 2022; Revised 29 December 2022; Accepted 4 January 2023; Published 7 January 2023. -- Correspondence author: Zully Ramos, email: z.ramosalvez@massey.ac.nz -- Academic Editor: Qiuyue Liu -- This article belongs to the Section Animal Genetics and Genomics (https://www.mdpi.com/journal/genes/sections/Animal_Genetics_Genomics ) -- FUNDING: his research was funded by the Regional Consortium for Innovation in Ultrafine Wool (CRILU), the European Union?s Horizon 2020 research and innovation program under the grant agreement n°772787 (Smarter) and the National Institute of Agricultural Research of Uruguay (INIA_CL_38: Rumiar). This study was supported by two Ph.D. scholarships (from the National Agency for Investigation and Innovation of Uruguay, ANII, and Massey University, New Zealand), awarded to Zully Ramos. -- LICENSSE: Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). --
Supplementary Materials The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/genes14010167/s1, Table S1: Enrichment analysis. |
Contenido : |
The aim of this study was to identify genomic regions and genes associated with the fiber diameter (FD), clean fleece weight (CFW), live weight (LW), body condition score (BCS), pregnancy rate (PR) and lambing potential (LP) of Uruguayan Merino sheep. Phenotypic records of approximately 2000 mixed-age ewes were obtained from a Merino nucleus flock. Genome-wide association studies were performed utilizing single-step Bayesian analysis. For wool traits, a total of 35 genomic windows surpassed the significance threshold (PVE > 0.25%). The proportion of the total additive genetic variance explained by those windows was 4.85 and 9.06% for FD and CFW, respectively. There were 42 windows significantly associated with LWM, which collectively explained 43.2% of the additive genetic variance. For BCS, 22 relevant windows accounted for more than 40% of the additive genetic variance, whereas for the reproduction traits, 53 genomic windows (24 and 29 for PR and LP, respectively) reached the suggestive threshold of 0.25% of the PVE. Within the top 10 windows for each trait, we identified several genes showing potential associations with the wool (e.g., IGF-1, TGFB2R, PRKCA), live weight (e.g., CAST, LAP3, MED28, HERC6), body condition score (e.g., CDH10, TMC2, SIRPA, CPXM1) or reproduction traits (e.g., ADCY1, LEPR, GHR, LPAR2) of the mixed-age ewes. Copyright: © 2023 by the authors |
Palabras claves : |
Body condition score; Fiber diameter; Gene; GWAS; Reproduction; Sheep. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
URL : |
https://www.mdpi.com/2073-4425/14/1/167/pdf
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Marc : |
LEADER 03484naa a2200289 a 4500 001 1063971 005 2023-03-15 008 2023 bl uuuu u00u1 u #d 022 $a2073-4425 024 7 $a10.3390/genes14010167$2DOI 100 1 $aRAMOS, Z. 245 $aGenomic regions associated with wool, growth and reproduction traits in Uruguayan Merino Sheep.$h[electronic resource] 260 $c2023 500 $aArticle history: Received 13 December 2022; Revised 29 December 2022; Accepted 4 January 2023; Published 7 January 2023. -- Correspondence author: Zully Ramos, email: z.ramosalvez@massey.ac.nz -- Academic Editor: Qiuyue Liu -- This article belongs to the Section Animal Genetics and Genomics (https://www.mdpi.com/journal/genes/sections/Animal_Genetics_Genomics ) -- FUNDING: his research was funded by the Regional Consortium for Innovation in Ultrafine Wool (CRILU), the European Union?s Horizon 2020 research and innovation program under the grant agreement n°772787 (Smarter) and the National Institute of Agricultural Research of Uruguay (INIA_CL_38: Rumiar). This study was supported by two Ph.D. scholarships (from the National Agency for Investigation and Innovation of Uruguay, ANII, and Massey University, New Zealand), awarded to Zully Ramos. -- LICENSSE: Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). -- Supplementary Materials The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/genes14010167/s1, Table S1: Enrichment analysis. 520 $aThe aim of this study was to identify genomic regions and genes associated with the fiber diameter (FD), clean fleece weight (CFW), live weight (LW), body condition score (BCS), pregnancy rate (PR) and lambing potential (LP) of Uruguayan Merino sheep. Phenotypic records of approximately 2000 mixed-age ewes were obtained from a Merino nucleus flock. Genome-wide association studies were performed utilizing single-step Bayesian analysis. For wool traits, a total of 35 genomic windows surpassed the significance threshold (PVE > 0.25%). The proportion of the total additive genetic variance explained by those windows was 4.85 and 9.06% for FD and CFW, respectively. There were 42 windows significantly associated with LWM, which collectively explained 43.2% of the additive genetic variance. For BCS, 22 relevant windows accounted for more than 40% of the additive genetic variance, whereas for the reproduction traits, 53 genomic windows (24 and 29 for PR and LP, respectively) reached the suggestive threshold of 0.25% of the PVE. Within the top 10 windows for each trait, we identified several genes showing potential associations with the wool (e.g., IGF-1, TGFB2R, PRKCA), live weight (e.g., CAST, LAP3, MED28, HERC6), body condition score (e.g., CDH10, TMC2, SIRPA, CPXM1) or reproduction traits (e.g., ADCY1, LEPR, GHR, LPAR2) of the mixed-age ewes. Copyright: © 2023 by the authors 653 $aBody condition score 653 $aFiber diameter 653 $aGene 653 $aGWAS 653 $aReproduction 653 $aSheep 700 1 $aGARRICK , D. J. 700 1 $aBLAIR, H. T. 700 1 $aVERA, B. 700 1 $aCIAPPESONI, G. 700 1 $aKENYON, P. R. 773 $tGenes, 2023, volume 14, issue 1, article 167. OPEN ACCESS. doi: https://doi.org/10.3390/genes14010167
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INIA Las Brujas (LB) |
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Registros recuperados : 6 | |
2. | | RAMOS, Z.; GARRICK , D. J.; BLAIR, H. T.; VERA, B.; CIAPPESONI, G.; KENYON, P. R. Genomic regions associated with wool, growth and reproduction traits in Uruguayan Merino Sheep. Genes, 2023, volume 14, issue 1, article 167. OPEN ACCESS. doi: https://doi.org/10.3390/genes14010167 Article history: Received 13 December 2022; Revised 29 December 2022; Accepted 4 January 2023; Published 7 January 2023. -- Correspondence author: Zully Ramos, email: z.ramosalvez@massey.ac.nz -- Academic Editor: Qiuyue Liu -- This...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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3. | | RAMOS, Z.; GARRICK, D.; BLAIR, H.; DE BARBIERI, I.; CIAPPESONI, G.; MONTOSSI, F.; KENYON, P. Nuevos parámetros genéticos para rasgos productivos y reproductivos del Merino Australiano. Producción Animal. Revista INIA Uruguay, Marzo 2023, no.72, p.22-25. (Revista INIA; 72).Tipo: Artículos en Revistas Agropecuarias |
Biblioteca(s): INIA Las Brujas. |
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4. | | RAMOS, Z.; BLAIR, H.T.; DE BARBIERI, I.; CIAPPESONI, G.; MONTOSSI, F.; KENYON, P.R. Productivity and reproductive performance of mixed-age ewes across 20 years of selection for ultrafine wool in Uruguay. Agriculture, 2021; 11(8):712. Doi: https://doi.org/10.3390/agriculture11080712 Article history: Received 9 July 2021, Revised 21 July 2021, Accepted 25 July 2021, Published: 28 July 2021.
Academic Editor: Milan Shipka.
This article is an open access article distributed under the terms and conditions of the Creative...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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5. | | RAMOS, Z.; BLAIR, H.T.; DE BARBIERI, I.; CIAPPESONI, G.; MONTOSSI, F.; KENYON, P.R. Phenotypic responses to selection for ultrafine wool in Uruguayan yearling lambs. Agriculture, 2021, v. 11, n, 2. DOI: https://doi.org/10.3390/agriculture11020179. OPEN ACCESS. Article history: Received: 28 January 2021; Accepted: 19 February 2021; Published: 22 February 2021. Acknowledgments: The authors thank the assistance of all staff of Glencoe Experimental Unit,
INIA Tacuarembó, SUL, SCMAU, INIA and CRILU.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Tacuarembó. |
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6. | | RAMOS, Z.; GARRICK, D.J.; BLAIR, H.T.; DE BARBIERI, I.; CIAPPESONI, G.; MONTOSSI, F.; KENYON, P.R. Genetic and phenotypic relationships between ewe reproductive performance and wool and growth traits in Uruguayan Ultrafine Merino sheep. Journal of Animal Science, 2023, Volume 101, skad071. OPEN ACCESS. https://doi.org/10.1093/jas/skad071 Article history: Received 13 July 2022; Accepted 06 March 2023; Published 07 March 2023; Corrected and typeset 14 April 2023. -- Corresponding author: z.ramosalvez@massey.ac.nz -- Issue Section: Animal Genetics and Genomics...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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Registros recuperados : 6 | |
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